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Two genetic maps with improved marker densities were recently developed for rainbow trout by INRA [ 12] and the NCCCWA [ 15].
The projection plots clearly showed that (i) marker density of the single durum wheat maps differed markedly along the linkage groups and (ii) the interpolated map effectively integrated the marker information from the component maps with improved marker density and genome coverage along the consensus chromosomes, with only a slight increase in linkage group total length.
This gave rise to two maps with improved density for either the small subunit (at an overall resolution of 3.3 Å) or the large ribosomal subunit (at an overall resolution of 3.1 Å), and these maps were used for the refinement of the atomic model as described below.
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This two-fold symmetrical 100S map with improved density at the interface was only used to model the interface.
To achieve the grid map with improved accuracy, the sonar information is further updated by using a Bayesian approach.
The local resolution for the extracellular loop is around 3.5 Å. e, The FSC curve for the 3D reconstruction of the cryo-EM map with improved local resolution for the extracellular loop of Notch-100.
The developed intraspecific linkage map defined map positions of 138 markers which included 101 new locations.Map integration with a previously published map was carried out which revealed an advanced map with improved density.
When applied to four barley linkage maps genotyped at nearly 3000 SNP markers, in less than one minute DAGGER produced a consensus map with improved fine structure compared to the existing barley consensus SNP map.
When applied to four barley linkage maps genotyped at nearly 3000 SNP markers, DAGGER produced a consensus map with improved fine structure compared to the existing barley consensus SNP map.
Both of these outbred mapping populations contain more genetic variation than do mice derived from crossing classical inbred lines, and they also have more recombination, permitting traits of interest to be mapped with improved resolution (Yalcin et al., 2010).
When TAX 307S (TAC plus FAC arms combined) was stratified by MAP-tau expression, we observed prognostic value for MAP-tau with improved median time to PFS for high MAP-tau expressers (n = 35) compared with low expressers (n = 73; 33.0 v 23.4 months) and a mean TTP of 31.2 months (log-rank, P = 0.010; Figure 4b), suggesting that this marker maintains prognostic value in metastatic patients.
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