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Interestingly, none of these CpGs maps to genes that have previously been reported to have a relationship with MS [ 7, 8].
A genome-scale analysis has demonstrated that differential DNA methylation preferentially occurs at regulatory regions and maps to genes enriched for differential expression during early development [ 140].
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Probes were mapped to genes based on UCSC Genome Browser database [16].
Here, except for two cases, all chimeric partners are mapped to genes.
For instance, a potential gene-gene interaction is observed if both partners of a chimeric sequence map to genes.
Finally, the ESTs were mapped to genes.
Reads mapped to genes represent tags filtered from background and mapped to predicted genes.
Variants were mapped to genes using the CGI gene files.
Among them, only 105 tags mapped to a unique gene and eight mapped to genes within the same family.
The numbers of human genes that map to genes of other species through HomoloGene are counted.
SNPs located in 11,558 genes were mapped to genes as described above.
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