Sentence examples for maps reads to from inspiring English sources

It maps reads to the reference genome with gapped alignment and scores these mappings with consideration for sequencing and alignment errors.

TopHat initially removes a portion of reads based on quality information accompanying each read, then maps reads to the reference genome.

TopHat maps reads to splice sites in a mammalian genome at a rate of ∼2.2 million reads per CPU hour.

Thus this second class of apparent rearrangements are where an aligner confidently maps reads to the 3' end or polyA of a mobile element in the reference genome.

The main new contributions of our work are the following: (i) we introduce the concept of a linear reference multi-genome that incorporates the catalogue of all known genomic variants with a reference genome (e.g. SNPs, insertions, deletions and inversions), and (ii) we develop a BWT-based read alignment algorithm, BWBBLE, that accurately maps reads to this multi-genome.

Hence, neither Bowtie nor MAQ should be used for mapping reads to quantify gene expression.

Gene expression profiling was measured by mapping reads to assembled sequences using SOAP [66].

One further limitation of Bowtie and MAQ is the random assignment of equally well mapped reads to the corresponding genes.

Tools for analyzing RNA-Seq data include TopHat [7], which analyzes mapped reads to identify splice junctions between exons.

We therefore assembled the mapped reads to obtain 19,752 NTRs.

Therefore, mapping reads to a reference genome has two limitations.