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The most widespread examples are the well-known Creative Commons licenses that are being used for text, images, audio, video productions, architectural design as well as for software and databases wherein information is stored on maps of genomes, proteomes and metabolomes and so forth.
This method compares physical maps of genomes with genetic maps by fitting a 4-5 term polynomial functions.
Optical Mapping creates high-resolution physical maps of genomes through the analysis of ensembles of single molecule ordered restriction maps.
For example, they have been used for the construction of physical maps of genomes by radiation hybrid (RH) mapping and/or genetic maps by identifying genetic variation in the amplified products [ 4, 22, 23].
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Microarray-based comparative genomic hybridization allows the construction of high-resolution maps of genome-wide copy number alterations.
Comprehensive maps of genome variability and population structure would facilitate genome-wide association studies of complex traits, functional gene investigations and the selection of appropriate donors for breeding purposes.
By deep sequencing cell-free DNA (cfDNA), isolated from circulating blood plasma, we generated maps of genome-wide in vivo nucleosome occupancy and found that short cfDNA fragments harbor footprints of transcription factors.
To visualize this process in molecular detail, we generated high-resolution maps of genome-nuclear lamina interactions during subsequent differentiation of mouse embryonic stem cells via lineage-committed neural precursor cells into terminally differentiated astrocytes.
Thank you for submitting your work entitled "A simple method for generating high‐resolution maps of genome wide protein binding" for peer review at eLife.
However high resolution maps of genome-wide methylation now show that cytosine methylation occurs throughout the genome, particularly in bodies of highly expressed genes [ 3], and up to 4.25% of cytosines in the human genome are methylated [ 1].
The mapping of genomes, he said, inspired scientists to use the same approach in studying proteins, metabolites and their biochemical connections, to name a few.
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