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Nauhaus, I. & Nielsen, K.J. Building maps from maps in primary visual cortex.
A tacit assumption of AC research has been that the multiplicity of functional maps in primary and secondary areas serves a refined continuation of subcortical stimulus processing, i.e. a parallel orderly analysis of distinct properties of a complex sound.
Similar methods yielded results on the formation of connectivity patterns underlying phenomena such as orientation preference, ocular dominance, and spatial frequency maps in primary visual cortex (area V1) [2, 6, 8, 9, 50 52].
The basic structure of receptive fields and functional maps in primary visual cortex is established without exposure to normal sensory experience and before the onset of the critical period.
Statistical connectivity postulates that the spatial statistics of the retinal ganglion cells together with a simple feed-forward connectivity scheme between the thalamus and the cortex seeds the structure of the early receptive fields and maps in primary visual cortex.
These results suggested that human auditory cortex conforms to the general primate model with two mirror-symmetric tonotopic maps in primary auditory core and belt areas that are joined at a common low-frequency boundary [13], [14].
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Multiple somatotopic representations of the face, lips, and fingers were localized and mapped in primary motor cortex (MI), ventral premotor cortex (PMv), polysensory zone (PZ), primary (SI) and secondary (SII) somatosensory cortex, parietal ventral area (PV) and 7b, as well as anterior and ventral intraparietal areas (AIP and VIP).
5. Almost half of the retinotopic map in primary visual cortex (V1) is devoted to mapping the fovea, the small central part of the retina where the light sensitive cells are packed most densely and where most of the color-sensitive cone cells are found.
Indeed recent studies found [88], [89] that the cochleotopic mapping in primary auditory cortex of mice is only present on a (relatively) large scale, whereas local neuronal populations show less organized cochleotopic gradients.
Linkage peaks at 6p25.3-p24.3 and 8p23.1-p21.3 that appeared to be specific to Hindu families, and at Xq21.1-q26.1 putatively specific to Muslim families, were likewise supported by refined mapping in primary genome scan families, but only Xq21.1-q26.1 was replicated across all Muslim families.
In addition, chromatin maps generated in primary cells and tissues represent only a snapshot of the development stage during which they were isolated.
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