Analysis of Hi-C and 5C contact maps has suggested that CTCF and cohesin are enriched at borders of topological domains (Dixon et al, 2012; Nora et al, 2012; Sexton et al, 2012; Phillips-Cremins et al, 2013) implying a role for cohesin in domain demarcation.
The human HZ strain was also resequenced, as optical mapping had suggested a possible error in the previously sequenced virB6 4 locus.
More commonly, QTL mapping has suggested that domestication-related traits are conditioned by a relatively small number of loci with large phenotypic effects (reviewed in [ 63, 64]).
What new questions about a historical event do you think seeing information spatially will allow you to ask? Related: Note: We love maps and have suggested myriad ways to use them in 13 years of Learning Network lesson plans.
Peptide mapping studies have suggested that the region corresponding to residues 7 19 of IAPP interacts with insulin.
Recent fate-mapping data have suggested that NFATC1 and GATA4 are markers of anterior-derived endocardial endothelium and distinguish it from posterior-derived vascular hemogenic endothelium (Misfeldt et al., 2009; Peterkin et al., 2009).
Previous QTL and association mapping studies have suggested TTG1 pathway genes as good candidates for trichome density variation [ 9, 13, 26], and recent studies have shown that natural variation in the R3 MYB repressor ETC2[ 26], the bHLH ATMYC1[ 27], and the R2R3 MYB GL1[ 10] underlies quantitative variation for trichome density.
Recent genetic fate-mapping experiments have suggested that, on the population level, progenitors expressing cut-like homeobox 2 (CUX2), another marker specific for callosal and other superficial-layer neurons, exclusively produce superficial-layer neurons (Franco et al., 2012), although conflicting results were subsequently reported (Guo et al., 2013).
Quantitative genetic analyses and QTL mapping based studies have suggested that both seed oil content and protein content are governed by the additive effect of genes involved [ 43].
Previous studies in mouse forelimb M1 using glutamate uncaging and laser scanning photostimulation (glu-LSPS) to map local circuits have suggested that neurons around L3/5A border zone can excite L2/3 neurons (Weiler et al., 2008; Wood et al., 2009; Wood and Shepherd, 2010) but lacked the spatial specificity to isolate a putative L4.
