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However, obtaining dense genotyping resolution for downstream fine mapping will require increased target coverage per individual.
Still, the lower-resolution mapping results for the adult plant color and coleoptile color traits in the RILs suggest that consistent gene-level mapping will require larger families and/or advanced multi-parent mapping approaches (Jordan et al. 2011).
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However, a detailed comparison of monkey and human maps will require measurements involving the same technique, since single-unit recording and BOLD imaging differ along many dimensions.
One possible explanation is that these two contigs are telomeric and placement of these contigs on the genetic map will require additional linked markers.
Cancer immunotherapy using protein-based therapeutics such as EGF-MAP will require repetitive administration, and thus the relatively high tolerability of CFPs make them superior to classical ITs.
Using these tools to generate circular maps will require repeated steps of updating the annotation details, generating the map, visualizing the map and inspecting the annotations to find errors.
Acting upon insights gained by the genomic road map will require a deeper understanding of how specific mutations cause tumors through reprogramming of signaling, metabolic, and epigenetic networks, particularly with regard to identifying therapeutic vulnerabilities (Cloughesy et al., 2014).
Searching for objects is an important everyday task; for instance, looking for an item on a supermarket shelf, a sign in a railway station or a place name on a map will require the swift detection of the 'target' object amongst an array of irrelevant 'distractor' items.
Traits showing non-additive variation or those controlled by rare alleles are also problematic for association mapping and will require a larger panel of germplasm and complementary genetic resources to permit dissection of these phenotypes.
However, mapping efforts will require a substantially increased and ongoing noise monitoring effort.
Resolving this possible mapping problem will require assembling a 454 read set for a model species since this will allow tests against the complete reference genome.
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