Sentence examples for mapping that mutations from inspiring English sources

Delineating gene function relies on the genetic principle established by decades of genetic mapping that mutations establish causality in phenotypes.

This study suggests that metabolic resistance mechanism is playing a significant role in pyrethroid resistance in An. funestus since we did not found any evidence either from direct sequencing or QTL mapping, that mutations in the target site are involved in pyrethroid resistance in An. funestus.

We show that Sal inhibits RNA synthesis in cells and that mutations that confer Sal-resistance map to RNAP genes.

Through the use of genetic models systems and the mapping of mutations that cause human diseases, it has been well-established that errors in these processes underlie a wide range of maladies, including birth defects, cancer, kidney disease, and neuronal degeneration.

10.7554/eLife.01754.007 Figure 4. Structural mapping of mutations that interfere with binding and CD4 downregulation.

Experimentally validated polymorphisms can serve as useful markers for mapping mutations that cause visible phenotypes.

Classical forward genetic studies were successful in mapping mutations that affected a trait (e.g. radiation sensitivity).

Map positions of mutations that were mapped in our project and cloned by other researchers are shown together with the ZMAP positions of the affected genes (publicly available from ZFIN [10]).

Therefore, we modeled the RIP1 DD structure based on the structure of Fas DD (PDB id 3OQ9) and mapped the mutations that might disrupt the formation of the RIP1 DD/FADD DD complex on the modeled structure of RIP1 DD.

Recently, it was discovered by genetic mapping and comparative sequencing that mutations in gidB can cause low-level resistance to streptomycin in S. coelicolor [28].

Doitsidou et al. (2010) developed a one step protocol that combines WGS and single-nucleotide polymorphism (SNP) mapping that further eases mutation identification in C. elegans.