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The higher percentage of the transcriptome that is specifically regulated in developing Pima fiber (17.24%) relative to TM1 (11.75%) is consistent with genetic mapping studies showing a decided bias for Pima alleles in interspecific mapping populations [ 10].
The results from our study are encouraging for laboratory-based association and linkage mapping studies, showing that this approach can yield results that are directly replicable in the field.
These results are consistent with both theoretical work and other QTL mapping studies, showing that many evolutionary differences are controlled by QTL with a range of effect sizes, including a small number of loci with substantial phenotypic effects (Orr 1999, 2005; Colosimo et al. 2004; Shapiro et al. 2004; Albert et al. 2008).
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The co-pelleting of purified N-GF and CA tubes, as well as domain mapping studies, showed that Mx2 directly recognizes CA assembles through its N-terminal 83-aa domain.
The gene mapping studies shown here prove that two or more related, but not identical var2csa-type genes exist in many P.falciparum isolates.
Using the known locations of homologous cDNAs and the RH-mapping techniques, mapping studies showed that the INTs are distributed among different human chromosomes for each tumour sample and are located in regions with the high levels of expression.
Genetic mapping studies showed Sc3-119 and Sc3-120 ISBP markers from ctg1034 were located within the terminal deletion bin 3BL-7 on chromosome 3B, a deletion bin known to contain two major C-bands [ 59].
Mutant and genetic mapping studies showed that the enzyme FAD2 was found to be mainly responsible for C18 1 and PUFA content although FAD3 also contributes to a limited degree to these traits [ 9, 18].
Also consistent with the stochastic nature of recombination, nucleosome mapping studies showed that RSSs do not occupy the same translational position on the nucleosome at either the Jκ or Jλ 1 regions, implying that different RSSs have the potential to become accessible in different cells.
Our mapping studies showed that the anti-SRP54 autoantibodies bind to the amino-terminal SRP54 N-domain and to the central SRP54 G-domain, but do not bind to the carboxy-terminal M-domain that is known to bind ER signal sequences.
For example, in the FLyB condition (BRAhigh), BRA binds close to many genes involved in posterior mesoderm development, consistent with fate-mapping studies showing that this tissue emerges from the posterior primitive streak, where Bra levels are higher (Lawson et al., 1991; Wilson and Beddington, 1997).
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