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Hence, the activity of formulating research questions in mapping studies is ill-defined, rendering it difficult for researchers who are new to the topic.
A major constraint to previous QTL mapping studies is the number of available polymorphic markers.
The aim of genetic mapping studies is to identify loci that underlie phenotypic variation.
The type of statistical gene mapping method used in gene mapping studies is critical for successfully identifying genes responsible for complex disorders.
Hence, further research on the usability of OLS in mapping studies is warranted.
The publicly available database of mapping studies is available through: http://www.herc.ox.ac.uk/downloads/mappingdatabase.ac.uk/downloads/mappingdatabase
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In this study, a pharmacophore mapping studies were undertaken for a series of phenylaminopyrimidines derivatives.
Systematic mapping studies are used to structure a research area, while systematic reviews are focused on gathering and synthesizing evidence.
To reveal novel insights into the inhibition of BCR-ABL tyrosine kinase, pharmacophore mapping studies were performed for a series of phenylaminopyrimidine-based (PAP) derivatives, including imatinib (Gleevec).
Systematic literature reviews and systematic mapping studies are becoming increasingly common in software engineering, and hence it becomes even more important to better understand the reliability of such studies.
The mapping studies are summarised in Additional file 3.
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