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Exact(6)
The mapping resolution was lower for the dominant suppressors, because those alleles can rescue when heterozygous.
As a result of map expansion, higher QTL mapping resolution was expected in the Syn10 population.
The long right tail of the distribution indicates that mapping resolution was low in some regions of the genome.
Given that the effective population size of Syn10 for QTL mapping was smaller than the Syn4 population (194 vs. 244), the extra increase in the mapping resolution was due not only to the higher recombination fraction in Syn10 but also the higher marker density.
Mapping resolution was lower than we anticipated.
Mapping resolution was assessed using simulations as describe in Materials and Methods.
Similar(54)
In addition, population development is time-consuming and mapping resolution is low (Kumar et al. 2014; Pascual et al. 2016).
If LD decays within a short distance, mapping resolution is expected to be high, but a large number of markers are required.
For linkage mapping in a biparental population with a size of hundreds, the mapping resolution is always in the 10 cM magnitude due to limited number of recombination that can be surveyed in such population sizes, not to mention that the effect sizes are usually grossly overestimated in such studies.
Another is that mapping resolution is usually severely limited.
Thus RH mapping resolution is six times more uniform than genetic mapping resolution.
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