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Large mapping populations have been generated from the NILs and fine-mapping of qNLB1.
The rice mapping populations have characteristics that would fit such a design well.
Furthermore, significant genetic × environment interaction, large number of genes encoding yield, and use of wrong mapping populations, have all harmed programs involved in mapping of QTL for high growth and yield under water limited conditions.
In previous studies, the rice varieties used to develop mapping populations have a HI of less than 0.5, and were thus not the ideal sources for genetic studies and high HI breeding.
One reason is that the same primary mapping populations have been used for QTL analysis in many different studies, mainly to avoid the time required to develop new mapping populations.
Previous efforts to meta-analyze different mapping populations have included taking the best P-value for each QTL interval and combining these values using Fisher's combination test [6] to assess the combined likelihood of ethanol drinking QTLs between C57BL/6J and DBA/2J.
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The lack of dense genetic maps, large high-throughput marker collections, and suitable mapping populations has limited gene isolation and breeding in blackberry.
In other species, integration of independent mapping populations has enhanced genetic resolution and provided comprehensive relational locus information for disparate marker and population resources [ 32].
SNP mapping of two candidate R genes in both the F1 NA6 × AU6) and p150/112 mapping populations has provided possible candidates for the major gene crown rust resistance QTL (LpPc1) on LG2 [ 14].
Because each mapping populations had an average of 174 progenies, it is possible that some of the mQTL of large effect may showed upward biased estimation (Beavis effect) of the phenotypic effects [ 33, 34].
Also, because corn is a major food crop, thorough investigation of mapping populations has been conducted leading to the identification of a multitude of grain yield QTLs [ 220- 233] which may lead to larger starch-derived ethanol yields.
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