Sentence examples for mapping of variants from inspiring English sources

Our mapping of variants on the predicted MUTYH structure based on homology modeling indicated that functionally deficient variants surrounded the [4F-4S] cluster.

Inconsistencies in residue numbering between sequence data sources further complicates mapping of variants to crystal structures and comparisons across the kinome.

The recent availability of chromatin immunoprecipitation (ChIP -seq data sets for M. tuberChIP -seqas extensively usedatar the mapping of variantsets

An extended mapping of variants was performed on the ENSEMBL human build V.54_36p with a software developed at the Cologne Center for Genomics to rank variants according to their presumed functional relevance.

Further, in the current setting of the Generation R Study, the small sample size resulting from defining well characterized ethnic groups (of non-European background) is insufficient to allow fine mapping of variants underlying complex traits, typically withholding weak genetic effects.

We have developed MU2A, a publicly available web service for variant annotation that reconciles differences between the genome and transcriptome, enabling the rapid and accurate determination of the effects of genomic variants on protein products, and the mapping of variants detected in transcripts to genomic coordinates.

A key advantage of TA is that it allows the mapping of variant surface trajectories due to phonetic context, stress, speech rate, etc. to a single invariant target as demonstrated in our previous studies in prosody modeling [3, 20 23, 31].

If an exon is completely contained in another larger exon, these are not merged but retained as individual exons, considered variant and then entered into a list maintaining the mapping of variant exons to distinct exons [ 24].

The work presented in this manuscript describes a detailed fine-mapping of variants across the IL18 locus, in a large UK SLE data set followed by a meta-analysis and analysis of a SLE GWAS cohort.

In this review, we highlight some of the key advances from the recent literature in which transethnic GWASs have been used for locus discovery, replication, fine-mapping or admixture mapping of causal variants associated with complex diseases.

Similarly, queries to retrieve variants from the Variation database are parameterized with the Core sequence identifier and desired range coordinate and return the properties and mapping coordinates of variants within this range.