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Furthermore, the specific haplotype block structure of the set of BXD RI strains allows the mapping of trait associated effects to specific chromosomal regions: a 4 Mb interval on Chr 12 correlated with relative fat content in epididymal adipose tissue, and a 4 Mb on Chr 17 correlated with lipid to protein ratio in the liver.
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Mapping of traits and testing in diverse genetic background.
However, hybridization also facilitates admixture mapping of traits that distinguish each species and the associated genes that maintain distinctiveness despite ongoing gene flow [2].
This information is particularly important in gene/QTL mapping of traits such as pod length and climbing habit to help discover candidate genes (Table S2).
The results also suggest the feasibility of using SNPs as markers in identification and targeted mapping of trait-associated genomic regions for stress tolerance and further for adaptive trait-specific association analysis in rice.
Physical distribution, degree of allele sharing, admixtures and introgression, and amino acid replacement of SNPs in 263 abiotic and 62 biotic stress-responsive genes provided clues for identification and targeted mapping of trait-associated genomic regions.
To drive the fine mapping of trait-regulating QTLs, the large-scale genotyping of simple sequence repeat (SSR) and prior discovered single-nucleotide polymorphism (SNP) markers in individuals of inter-/intra-specific mapping populations employing multiple high-throughput genotyping assays are found to be fairly suitable in chickpea.
Interestingly, the fine mapping of trait-associated QTLs has now become simpler and easy to accomplish with advent of a next-generation sequencing (NGS -based geNGS -basedy-sequencing (GBS) assay that demonstrated its efficacy by simultaneous discovery and genotyping of SNPs in mapping individuals at a genome-wide scale.
In summary, we demonstrate here the use of the DO mice for high-resolution mapping of traits related to atherosclerosis.
While Varroa mites are not tractable to controlled crosses, associative mapping of traits such as reproductive success on different hosts remains an attractive possibility, as is the mapping of resistance traits in honey bee.
The main purpose of this work was to develop dense genetic linkage maps for mapping of traits related to yield and resistance in willow.
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