Sentence examples for mapping of mutant from inspiring English sources

Genetic mapping of mutant loci was performed as described [18].

Mapping of mutant loci was performed as described previously (Davis et al. 2005).

The development of powerful new methods for DNA sequencing enable the discovery of sequence variants, their utilization for the mapping of mutant loci, and the identification of causal variants in a single step.

Other methods that have been proposed for the mapping of mutant loci in the zebrafish include half-tetrad analysis with microsatellite markers, genome scanning with SNPs and microarray based SNP mapping.

The manual concludes with a section on classical strategies for the mapping of mutant alleles or transgenic constructs, including simple crosses with multiple balancer lines, deletion and meiotic mapping, and some of the complications that may arise during complementation tests (e.g., transvection, nested genes, noncoding RNA loci).

This required isolation and genetic mapping of mutants that could not grow without methionine, leading to an interest in the mechanism of recombination, the process that ensures that new combinations of genetic variants are transmitted from one generation to the next.

The introduction of high-throughput sequencing techniques and the development of databases containing genomic sequences and single nucleotide polymorphism (SNP) of several inbred mouse strains have allowed the generation of SNP panels that facilitate efficient mapping of mutants and subsequent gene identification by sequence analysis.

Mapping of mutants that had an effect on ATP potency onto the structure shows that residues predicted to form the ATP-binding pocket are clustered at a groove that forms at the interface between two subunits (Kawate et al., 2009; Evans, 2010).

This marker development strategy enables rapid fine-mapping of mutants in any laboratory equipped for basic molecular biology techniques.

In contrast to the ICP-AES data, no bound Ni2+ ions are observed in the electron density maps of mutants MA1 or mutant MA1B.

Mapping of the mutant lines during the course of stock maintenance reduced the size of the region harboring the mutant alleles, allowing us to eliminate an additional nine replacement variants from further consideration (Table 2).