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Dr. Hood, one of the founders of the Institute for Systems Biology in Seattle, was a pioneer in the field of automated gene sequencing, and one of his graduate students at the time, Trey Ideker, was exploring whether it was possible to automate the mapping of gene interactions.
Today, science has evolved to the mapping of gene families, and to the systematic determination of the interactions between gene products.
Recent advances in light microscopy technology enable comprehensive analyses of cellular dynamics during zebrafish embryonic development, systematic mapping of gene expression dynamics, quantitative reconstruction of mutant phenotypes and the system-level biophysical study of morphogenesis.
Our results provide the basis for further mapping of gene coordination structure onto specific functional brain networks.
This web-based entry tool allows for the mapping of gene expression data into relevant pathways based on their functional annotation and known molecular interactions [23] [25].
Phylogenetic mapping of gene expression patterns on a molecular phylogeny suggests that differential expression along the primary body axis is a primitive feature of the Nematostella Hox-related genes, while differential expression along the secondary body axis evolved afterwards.
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Mapping of gene-trap insertion sites and statistical analysis were performed as previously described (Carette et al., 2011).
This facilitates mapping of gene-based markers, such as ESTs, which are commonly low in polymorphism [ 12] and are valuable tools for interspecies comparative studies.
Mapping of gene-based markers in chickpea will also add more anchoring points to align genomes of chickpea and other legume species.
Therefore, one must consider the phenotype analysis as a general thematic picture of the functional consequences of our cDNA sequences rather than as a one-to-one mapping of gene-phenotype associations within our cDNA sequences.
An F6 RIL population, derived by single-seed descent from a single F1 plant from cross H 77/833-2 × PRLT 2/89-33, was used for mapping of gene-based markers.
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