Sentence examples for mapping of epitopes from inspiring English sources

Mapping of epitopes is a crucial step for the study of immune pathways, the engineering of vaccines and the development of immunoassays.

Mapping of epitopes was done using pools of overlapping peptides based on the consensus clade B sequence spanning the entire HIV proteome (Los Alamos immunology database).

Nowadays, more sophisticated in silico approaches exist, which are powerful tools to allow mapping of epitopes from virtually all HLA allotypes.

Another extensive source of epitopes and antigens including neuraminidase of influenza A viruses is the immune epitope database (IEDB) [ 47] and the complete mapping of epitopes for the new H1N1 NA sequence is available at.

Accurate in silico prediction of linear B-cell epitopes is a highly desirable goal as it is often the important first step in computational mapping of epitopes on pathogen proteins and in the design of immuno-diagnostics and vaccine development.

21 Currently, the rapid expansion of biologic databases and computational programs facilitate more elaborate research in postgenomic sequence analysis, characterization of sequence variability, and especially, the mapping of epitopes and computer-aided rational vaccine design.

Mapping of epitope(s) recognized by anti-kinectin antibodies may shed light on the question of whether different autoepitopes reside within the kinectin molecule recognized by sera from different diseases.

Phosphosite mapping of epitope-tagged PSKR1 (phytosulfokine receptor 1) from Arabidopsis thaliana plants identified Ser and Ser in the JM (juxtamembrane) region and probably Ser and/or Ser in the AL (activation loop) as in planta phosphorylation sites.

The fine-mapping of epitopes, typically 9 amino acid (AA) long but ranging from 8 to 11 AA, together with data on their binding properties to HLA molecules, has allowed definition of HLA class I allele-specific sequence motifs that are able to prime virus-specific CD8+ T-cell responses.

This includes strong corroborative evidence for conformational specificity and the need for a non-linear epitope for conformational antibodies, precise mapping of small epitopes, and information about cross reactivity within and across species.

It should be noted that epitope competition assays only offer an approximate mapping of binding epitopes rather than any precise level of molecular detail.