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The application of the method to PGC1 BD and SCZ datasets suggests that JEPEG has the potential to improve both gene detection and fine mapping of challenging regions, such as MHC for SCZ and ITIH cluster for BD (SCZ).
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The practical applications suggest that JEPEG has the potential to aid fine-mapping of challenging regions.
In addition, the detailed mapping of challenges and framework properties reveals that an open-source approach is a fundamental condition for complying with scientific standards.
General findings of the detailed mapping of challenges and properties are that an open-source approach is a pre-condition for complying with scientific standards and that approaches to tackle the challenges complexity and uncertainty counteract each other.
By using MAXMap we draw the schematic map of challenges in implementing self-assessment and peer-assessment in writing courses from the perspectives of ELT learners.
The kinetics of MAP shedding in feces of challenged animals showed a peak around 130 days post-challenge, irrespective of vaccination status.
Developing a detailed description of subsurface fracture map is challenging for geothermal and petroleum industry due to a number of reasons: It is often difficult to obtain sufficient hard data such as borehole images and core description.
Conclusions: Applied analyses results suggest that JEPEG complements commonly used univariate GWAS tools by: (i) increasing signal detection power via uncovering (a) novel genes or (b) known associated genes in smaller cohorts and (ii) assisting in fine-mapping of challenging regions, e.g. major histocompatibility complex for schizophrenia.
This makes multiparametric mapping challenging.
The prospect of triple-digit oil prices has redrawn the economic and political map of the world, challenging some old notions of power.
Fig. 1 Heat Map of CASMI Challenges 1 81 (negative mode).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com