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However, a comprehensive mapping of cancer dependencies has lagged behind and the discovery of therapeutic targets for counteracting tumor suppressor gene loss is needed.
High-throughput genome sequencing of bisulfite-treated DNA has enabled the mapping of cancer methylomes genome-wide [ 8].
Gene bodies have attracted almost no attention in the mapping of cancer methylomes and this might need to change.
The biorecognition conjugates, like hyaluronan (HA, a nonsulfated polysaccharide), have played very important role in the mapping of cancer lymphatics to enhance therapeutic outcomes.
M. spretus strains are also cancer resistant in comparison to several M. musculus strains and have been utilized for mapping of cancer susceptibility loci [ 11- 16].
In addition, epitope mapping of cancer and pathogen-associated proteins is a commonly employed method for the identification of relevant CTL epitopes [ 35, 36].
Similar(46)
This structure also allowed for the mapping of cancer-causing mutations within the kinase domain, suggesting that a loss of kinase function may contribute to tumorigenesis.
Mapping of cancers in adolescents and young adults was based initially on specific morphology codes (sometimes in combination with topography codes); thereafter, the mapping was based on groups and subgroups within the Birch et al classification (see Appendix 1).
Maps of cancer incidence and mortality, computed on a global scale by the International Agency for Research of Cancer, are readily interpretable (Ferlay et al. 2001).
What brought them together was anger and frustration over the state's recently released maps of cancer incidence county by county.
Hanging over the publication of more detailed maps of cancer incidence are fears that possible polluters in the areas with the highest rates will sue to suppress data or to erase the implication that they are responsible for causing the cancers.
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