Sentence examples for mapping of binding from inspiring English sources

The mapping of binding site was carried out using the following parameters, Binding equilibrium constant Initial rate of perturbation Magnitude of the perturbation Among these parameters, the last two can be either calculated from model equations and fitted parameters or obtained directly from experimental data.

Malhotra, D. et al. Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis.

Our understanding of protein evolution would greatly benefit from mapping of binding landscapes, i.e., changes in protein-protein binding affinity due to all single mutations.

Such applications include the design of novel binders and inhibitors, the enhancement of affinity and specificity, and the mapping of binding epitopes.

The formalism presented here is likely to be useful in the design of bioactive ligands to a specific target protein and in the quantitative mapping of binding epitopes and interfaces between molecules in complexes.

We performed in parallel, inter-species conservation analysis of the promoter and mapping of binding sites for known transcription factors (Fig. 4).

Mapping of binding-induced changes between the E2·E3BP core and PDK1 and PDK2 creates a rich source of starting points to better define critical regions that could serve as targets for future drug design.

The CoMFA and CoMSIA contour maps, MOLCAD-generated surface maps of binding site and docking poses were found complimentary with each other in terms of electrostatic, lipophilicity, and hydrogen-bonding potential.

A precise map of binding sites for transcription factors and other DNA-binding proteins is vital for deciphering the gene regulatory networks that underlie various biological processes [ 1- 4].

Parametric maps of binding potential (BPND) were generated with the simplified reference tissue model using the two input functions, and were compared with each other.

A precise map of binding sites for transcription factors (TFs), core transcriptional machinery, and other DNA-binding proteins is necessary to decode the gene regulatory networks and their contribution to developmental processes and human disease [ 1].