Haplotypes associated with different levels of gene expression were mapped in unrelated individuals, an approach that has proven powerful to identify cis-acting loci [ 46].
This fact seriously limits the usefulness of these maps for assisting breeding, especially considering that a number of important carrot traits, including nematode resistance [ 10], anthocyanin pigmentation and reduced-sugar accumulation [ 4], have been mapped in unrelated genetic backgrounds.
For comparison purposes, linkage analyses were also performed in two mapping populations unrelated to population 70349 but also segregating for root and petiole purple pigmentation.
Considering that many factors, such as the environment and the genetic background, affect QTL detection, QTL comparative mapping between unrelated families in different environments through time represents an interesting strategy to highlight consensus regions of importance for a given trait [ 18, 37].
The consensus map positioned 2673 of 3938 SNPs (68%) genotyped in unrelated individuals from the P. taeda ADEPT2 population and 2829 of 4854 SNPs (58%) in the CCLONES multiple-family pedigree.
In contrast, association mapping is based on natural populations, searching for genotype to phenotype correlations in unrelated individuals.
In spite of this, we expected the resulting genealogies to resemble those in QTL mapping experiments involving unrelated individuals, such as Genome Wide Association Studies GWASS).
In unrelated news, I need a beer.
In unrelated news: poor Liverpool.
Thus, a specialized region (low in unrelated variety) is in fact a driver of enterprise productivity.
