Sentence examples for mapping in laboratory from inspiring English sources
One approach that has been used to narrow individual QTL intervals is in silico haplotype mapping in laboratory inbred strains [14], [15].
Nonetheless, these markers still have potential for use genetic mapping in laboratory colonies or investigating Cx. pipiens complex populations from other geographic areas.
These results demonstrate that GWA scans using dense SNP maps in laboratory mice are a powerful tool for the refinement of previously identified QTL regions.
The use of dense SNP maps in laboratory inbred mice has proven successful in the refinement of previous QTL regions and the identification of new genetic determinants of complex traits [4] [8].
Our dataset does exhibit systematic bias, in that more traits mapped in natural strains were under biotic selection: 36% of natural traits were biotic, while only 16% of traits mapped in laboratory strains were biotic.
In spite of these caveats, although we included both natural and laboratory ecotypes in all subsequent analyses, we conducted all analyses presented here on a subset of data including only QTL detected in natural accessions and excluding all traits mapped in laboratory strains.
Rabbits have been found to be naturally susceptible to Mycobacterium avium subsp. paratuberculosis (Map) infection in the wild [ 1– 4], to Mycobacterium avium subspecies infection in natural conditions, specifically Mycobacterium avium subsp. avium (Maa) in pigmy rabbits [ 5] and moderately susceptible to Map in laboratory conditions [ 6, 7].
LL measured the oil traits; FS extracted DNA and RNA of the QTL mapping population; FS and PL participated in laboratory and field work for data collection.
The increasingly automated solutions used in the studies described above relied on either the production of optical maps in the Schwartz laboratory, or on the commercial OpGen Argus platform [ 11, 12].
The IL1B primers we tested failed to amplify correctly, but other chicken EST markers located near IL1B, whose position is 113.3 Mb on HSA2q, had been used in another mapping project in our laboratory [ 16].
Field mapping and laboratory analyses of samples were the stages adopted in the course of this research.
