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The resulting three-dimensional mapping has yielded a "visual representation of the evolution of the universe," said Alexander Szalay, a professor at Johns Hopkins University.
Comparative mapping has yielded important insights into patterns and mechanisms of genome rearrangements in plants, mammals, fruit flies, and yeasts [ 5- 10].
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To explore the time course and the topographical localization of the observed spectral amplitude differences between conditions, the signals across the recording interval were multiplied with cosine windows at their beginnings and ends and filtered in the frequency ranges in which the statistical probability mapping had yielded significant effects.
If atomic models of subunit structures in the complex are available from x-ray crystallography or homology modeling studies, fitting these atomic models into cryoelectron-microscopy maps has yielded pseudoatomic models of macromolecular complexes.
The approach of identifying hinge regions for domain fitting to the suilysin pore map has yielded a pseudo-atomic model that goes beyond the earlier rigid body fitting to pneumolysin (Tilley et al., 2005).
Interval mapping focusing on the individual mutations has yielded significant quantitative trait loci (QTL), but no common modifiers across the three mutations, and no significant interactions (Oliva et al. 2014; Frankel et al. 2014; data not shown).
After the software has yielded its stunning map, he develops hunches about which connections are worth exploring further.
The translocation mapping in a case of isolated BRAHD has yielded two plausible candidate genes that merit further investigation.
This type of comparison has yielded multiple informative modules that have been used to perform comprehensive maps in cancer [ 41], and here we apply these tools to diabetes.
Their feistiness has yielded results.
Harmony has yielded to discord.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com