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These results suggest the high quality of our sequencing datasets.> After read mapping, gene expression was calculated using Cufflinks and the abundances of genes were expressed as FPKM (Fragments per kilobase of transcript per million fragments mapped) [ 53].
In recent years, genomic resources have been developed to enable comparative genomics, quantitative trait locus mapping, gene expression analysis, and the creation of transgenic lines and targeted knock-outs2,3,4,5,6,7,8,9.
Biological insights have resulted from these sequencing initiatives as well as from genetic mapping, gene expression profiling and gene discovery research over nearly two decades.
Once enumerated, maximal cliques are widely used to solve problems in areas such as 3-D protein structure alignment, genome mapping, gene expression analysis, and detection of social hierarchies.
Their applications range from medical diagnosis, homeland security and genetic counseling to natural language understanding, search engines and mapping gene expression data.
Mapping, gene expression, and population genetic work all identify a single gene, optix, that controls extreme red wing pattern variation across multiple species of Heliconius.
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Technologies to visualize and map gene expression in situ create a stir.
Analyses of Connectivity Map gene expression data, published texts and a cell-based screening assay revealed thousands of putative and potentially clinically beneficial interactions.
Ebert and Regev have mapped gene expression in blood stem cells as they mature into different types of blood cells.
A classic study mapped gene expression activity in 5 spatial regions across 3 developmental stages [1], yielding 15 spatiotemporal snapshots.
OPT can be used to dissect mutant phenotypes and to globally map gene expression in both 2D and 3D.
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