These high-resolution mapping experiments allowed the assessment of the LCR 22‐2 genes copy number and relative arrangement.
Moreover, data obtained from IS mapping experiments allowed us to investigate and quantify the effect of IS5 on the transcriptional activity of motility and chemotaxis genes in the genome of E. coli MG1655.
This was done using exclusively the few Passiflora gene sequences deposited in public databases as probes in macroarray hybridizations, and the corresponding BACs used in FISH experiments allowed us to map four genes to three chromosomes of the species.
Data obtained by recording and manipulating electrical activity in the substantia nigra were consistent with this model and further experiments allowed this microcircuit to be mapped in detail.
The combination of methyl-TROSY and paramagnetic spin label NMR experiments allowed Kato et al. to map the nucleosomal surface bound by high mobility group nucleosomal protein HMGN2.
The mentioned controller, developed specifically for these experiments, allowed detecting the footsteps of the subjects and mapping these to the real-time sound synthesis engine.
This approach is particularly valuable because it allows for mapping experiments even in the absence of any prior knowledge of polymorphisms between the parents of a mapping population, does not require extensive laboratory manipulation and can be performed using a single hybridization replicate.
The results of protein cleavage studies, immunologic epitope mapping experiments, chemical modifications, and glycosylation-scanning and cystein-scanning mutagenesis allowed for the construction of a working structural model of GLUTs that is based on 12 transmembrane segments.
The inclusion of dilution samples and referencing hairpins allows standardization, validation, and deeper analysis of structure mapping experiments at negligible additional cost.
DNA crosslinking experiments were performed by S.B. and M.U., peptide mapping and site-directed mapping experiments were done by S.B., and histone crosslinking experiments by S.P., M.U.
