Sentence examples for mapping bias was from inspiring English sources

Instead, we found evidence that read mapping bias was responsible for those errors.

Thus, no real mapping bias was identified towards any of the non-syntenic barley or rice chromosomes.

5′-3′ mapping bias was comparable to that of RNA-seq data for oocytes in previous studies (Park et al., 2013) (supplementary material Fig. S2).

After demonstrating that there is an overestimation of reference allele frequency in the 1000G SNPs (see the section Results), we hypothesized that mapping bias was the underlying cause.

If mapping bias was influencing allele frequency estimates, we expected that, for SNP positions with overestimation of the reference allele frequency in the 1000G, the alternative alleles would be flanked by additional alternative alleles (and thus have a greater mismatch count against the reference sequence).

Mapping bias was indicated if more reads could be mapped based on the 'two genome approach'.

We found a bias toward overestimation of reference allele frequency for the 1000G data, indicating mapping bias is an important cause of error in frequency estimation in this dataset.

If REF allele mapping bias is driving errors in frequency estimation, it is expected that sites with an overestimation of REF allele frequency would present the following pattern: windows carrying the REF with fewer differences to the reference genome than sequences centered on the ALT alleles.

Reference allele mapping biases are, however, more likely to affect ASE analysis, producing a pattern of greater expression in the reference allele.

The map bias is relative to the NBS value.

Therefore, the mapping efficiency bias was unlikely to explain the large number of the freshwater-increased GCNVs.