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In a second step the presence of a given EP map as identified in the group-averaged data was verified statistically in the EPs of the individual subjects.
Ashkenazi Jews have been a well-studied group for the purposes of gene mapping as well as identifying genetic and other factors associated with exceptional longevity due to their genetic as well as socio-cultural homogeneity, although their survival and causes of death are similar to those reported for the majority U.S. population [ 48].
The results of the systematic mapping, as well as identified future trends, are presented in the "Results and discussion" section.
We sought to achieve census-level representation across all ages within Kanungu District's 10 Batwa settlements (mapped in Figure 1) as identified by partners from the Batwa Development Program and Bwindi Community Hospital.
Resulting proteins were randomly phosphorylated at S, T, and Y residues with probabilities as identified after mapping all experimental phosphorylation sites onto A. thaliana protein sequences in case of experimental sites.
Using gene expression microarray technology, Suarez-Merino et al. [62] found the transcripts of four genes mapping to 22q12.3 22q13.33, namely C22ORF2, as identified by Karakoula et al. [51] mentioned above, FBX7, CBX7, and SBF1, to be under-expressed in pediatric ependymomas as compared to normal brain controls.
The hierarchical tree was searched for neighboring and parental clusters where both clusters (denoted A and B) map to variant gene families as identified in Table 1.
We restricted this search to tissue-specific contigs, as identified from the mapping step, plus the singletons from each tissue.
Reproducibility between replicates was determined by the eQTL map position identified, as well as the confidence in the eQTL (p-value).
Furthermore, we treat 'already mapped' neighbors in the same way as identified nodes (URIs and literals).
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