Sentence examples for mapping and resequencing from inspiring English sources

The chr9p signal is idiosyncratic and will undoubtedly require extensive rounds of fine mapping and resequencing before the causal functional unit(s) can be determined.

The recent release of the bovine genome [ 70], a closely related species, will greatly aid mapping and resequencing of sheep genes responsible for parasite resistance.

There is also no evidence that rs3781637 is linked with any functional variant now, but future fine mapping and resequencing of the MTNR1B gene may detect such functional variants.

Fine-scale genetic mapping and resequencing of the region surrounding rs2981582 resulted in the identification of up to eight variants in a linkage disequilibrium block (LD block) within intron 2 of FGFR2 most strongly associated with increased breast cancer risk, including SNP rs2981578 [ 1, 5, 7].

The quality of FASTQ genome re-sequencing data delivered from the University of Utah was checked using the FastQC program; data passing the quality control were imported into the CLC Genomics Workbench 5.5.1 for genome mapping and resequencing analyses to identify the potential small genetic changes such as SNP and indels in the mutant strain.

Finer mapping and deep resequencing of the sex determining region in F. chiloensis is underway to test these ideas.

There is no doubt that additional, denser genotyping, admixture mapping and deep resequencing will refine current loci and uncover new ones.

Combining information from the genetic linkage map and the resequencing data on the genetic divergence among the two parents, we constructed a soybean linkage map and observed the presence of recombination hotspot and coldspot regions and of several large genomic regions that were genetically fixed.

Though targeted gene mapping efforts using microsatellite markers and resequencing of candidate genes have resulted in discoveries for traits with simple hereditary patterns, the study of complex disease and behavioral phenotypes has proven to be very challenging.

Large-scale fine-mapping and resequencing efforts are needed to catalogue and evaluate the genetic variation from the full allele spectra in associated regions.

Understanding how coding and non-coding variants together can affect disease risk through such fine-mapping and resequencing efforts is arguably the most challenging and exciting area for genomic medicine today, because it offers opportunities for drug discovery or repositioning (by targeting specific mutations, signaling receptors or biological pathways).