Sentence examples for mapping and replication from inspiring English sources

Our results provide a basis for the design and interpretation of GWA replication studies and point to the importance of a clear distinction between fine mapping and replication after GWA.

Subsequent fine mapping and replication in an independent sample of 454 French/Canadian CD trios supported the authenticity of the NELL1 association.

On Chromosome X, primary and refined mapping and replication studies suggested a broad region of linkage to VL that was specific for Muslim families.

Only those chromosome regions that achieved LOD≥1 (nominal P≤0.02) in analysis of all families and/or the religion-specific analysis were taken forward in refined mapping and replication studies.

All genomic positions in the genetic maps and replication-timing profiles were converted to the versions of the human genome (hg19) and mouse genome (mm9) from which the alignments were computed using the liftOver tool available at UCSC (http://genome.ucsc.edu/cgi-bin/hgLiftOver).

Finer mapping and further replication in larger cohorts will be needed to ascertain their relationship with CRC susceptibility.

Using FISH mapping and DNA replication timing assay, we found that a large centromeric portion of Z chromosome, comprising a majority of the chromosome, was inverted during evolution.

The IIBDGC is a good example of what can be achieved by performing large meta-analyses, and it is currently performing dense fine-mapping and replication studies to identify causal variants and additional risk loci in CD.

The recent growth in publicly available data sets that contain both whole genome association data and a wealth of phenotypic data, serves as an excellent resource for fine mapping and candidate gene replication.

Furthermore, 10 previously identified ASD candidate genes (ALAS1, CSMD3, FOXP2, GABRG1, GBE1, GRM8, FBXO33, IMMP2L, SLC4A10 and ACO2) were located in rHH regions in both the discovery and replication HH mapping analyses [size adjusted p = 0.001, OR = 2.99 (1.5.905.90)].

Ten ASD candidate genes (ALAS1, CSMD3, FOXP2, GABRG1, GBE1, GRM8, FBXO33, IMMP2L, SLC4A10 and ACO2) occurred in rHH regions in both the discovery and replication HH mapping analyses To investigate our findings further, we performed a replication study on an additional 1,182 independent AGP trios.