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Mapping a novel mutation to a well defined chromosomal region is an important step in genetic analysis.
After mapping a novel locus for FADS/LMPS to chromosome 19, we identified a homozygous null mutation in the RYR1 gene in a consanguineous kindred with recurrent LMPS pregnancies.
Considering that ~96% of the markers (1298 markers out of 1358) were mapped in the 81 RH groups, one can estimate the probability of mapping a novel marker of interest in one of the existing RH group to be 96%%.
In this paper we described Contribution Mapping, a novel approach to research monitoring and evaluation.
In order to guarantee one-to-one mapping, a novel iterative bi-directional mapping strategy was proposed.
In this article we will describe Contribution Mapping, a novel approach to research monitoring and evaluation that focuses on processes and contributions (instead of products and impacts).
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We then introduced and mapped a novel climatic statistic, "safe winter chill", the 10% quantile of the resulting chilling distributions.
For example, we fine mapped a novel obesity QTL to a region of approximately 700 Kb (33.98 34.71 Mb) on proximal chromosome 9, which covers two candidates: Kirrel3 and A130066N16Rik; and mapped a novel QTL to a region of approximately 100 Kb (56.28 56.37 Mb) on distal chromosome 19, which covers Habp2 and Nrap.
Using Caenorhabditis elegans, we map a novel sensory neuron circuit motif that encodes odor concentration.
This study mapped a novel association to the ABO blood group system with SNPs that strongly tag the O allele.
Cirak et al. (2009) mapped a novel disease locus to chromosome 7p21 in a family with loss of α-dystroglycan glycosylation.
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