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Knowing them all would be, for students of the immune system, rather like mapping a genome is for more general biologists.A Human Vaccines Project would also try to work out how best to drive an effective response to pathogens that the immune system struggles with, such as HIV, tuberculosis and malaria.
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The mapped SSR markers were then used to construct a map to integrate the A genome map for B. napus with that of B. rapa genetic maps.
In our study, 1,755 SNPs mapped to the A genome, whereas 2,073 SNPs mapped to the C genome.
The map reported here is the first physical map for Brassica "A" genome based on the High Information Content Fingerprinting HICFF) technique.
If only these SNP markers had been used for linkage map construction, then an A genome diploid map would have been constructed within a tetraploid context!
AMID the brouhaha surrounding the Human Genome Project and its commercial rivals, the fact that there is more than one way to map a genome has got rather lost.
Extrapolated onto the whole map, a genome size of about 426 Mb is calculated.
Therefore, the 454-derived unigenes map a genome location better than assembled ESTs produced by conventional sequencing.
In comparison to our RH map, a genome ratio of 37.65 cR12,000/cM was calculated, which corresponded to the value obtained in our initial study (42.8 cR12,000/cM, [ 8]).
This is the first whole genome physical map representing the Brassica "A" genome.
All the A genome specific markers mapped on A genome LGs at the expected positions vis-à-vis BRAD database [ 26].
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