In 2000, the mutation that was causative for two mouse models of polycystic kidney disease, named kat (for kidney, anemia, testis) and kat 2J, was mapped to the murine Nek1 gene (16, 17).
The sequence reads were of 36 or 50 bp in length and mapped to the reference murine genome assembly NCBI37/mm9 using Bowtie.
Gnb1 maps to murine chromosome 4 (at 15 Mb) and GNB1 maps to human chromosome 1p36.33.
Although originally mapped to 88 cM on murine chromosome 5 [ 2], more recent data locate the microsatellite used to define lbw3 at 81 cM (discussed later).
A protein network similarity matrix (PNSM) was built and mapped to the ontogeny of the murine immune cells gene expression profile as catalogued at ImmGen.
Murine genes were mapped to their human homologues using a purpose written Python program using data from the database, HOM_AllOrganism.rpt, available from the Jackson Laboratory (ftp://ftp.informatics.jax.org/pub/reports/HOM_All Organism.rpt).rpt
Furthermore, 457 out of 2,121 circRNAs in humans were found with circular orthologues in murine, and 69 murine circRNAs can be exactly mapped to the start and stop sites of human circRNAs (Memczak et al., 2013).
To verify the compatibility of FPKM calculated using conventional method (RNA-seq reads mapped to the genome) and FPKM calculated using de novo contigs, we assembled RNA transcripts using murine RNA-seq reads from liver, kidney, and brain.
The murine PREB gene has been localised to the proximal end of chromosome 5 [ 26] and a partial human cDNA encoding PREB was cloned from brain and mapped to 2p23 [ 34].
