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Figure 1 illustrates how input content is mapped to candidate templates and produces a sequence of pages with associated content.

Finally, allele frequency data downloaded from HapMap [40] were mapped to candidate variants in dbSTEP (HapMap phase 3).

17,505 (31%) of the unigenes were mapped to candidate Gene Ontology (GO) terms.

Assembled unigenes that had significant (e-5) BLASTX matches to the nr database were mapped to candidate GO terms.

Using GBA candidate genes, we had higher average AUC in 10-fold CV, the average is 0.705 (T = 1) and 0.730 (T= ∞) in models including all the SNPs that are mapped to candidate genes, and 0.687 (T = 1) and 0.715 (T= ∞) after removing SNPs with p value <5 × 10−7.

Second, we tested trait and gene-specific hypotheses, repeating the analysis above, but using only the number of QTL and the marker intervals for the actual traits that mapped to candidate genes.

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We set three stringent criteria for identifying cis-NAT siRNAs, 1) the enrichment of 21-nt reads within a candidate locus; 2) presence of reads uniquely mapped to the candidate locus, and 3) more than 10 reads from the locus.

In the second step, the expression profile filtering was based on miRNA expression pattern using the abundance of the miRNA candidates in each library and the distribution of reads mapped to a candidate pre-miRNA according to Meyers et al. relaxed criteria [ 42].

*a The average number of deep sequencing reads mapped to each candidate sRNA: total number of reads divided by the length of the candidate sRNA, to compare the relative expression levels.

For the specific traits that actually mapped to the candidate genes, however, a slightly different picture emerges.

In addition, some Chr9 SNPs were included to determine whether the Uns-7 contig mapped to the candidate region of Chr9 that had been identified previously in the F4 generation.

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