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The most common cancer mutations map to single arginine residues in the catalytic pockets: IDH1 (R132) and IDH2 (R172 or R140) [56, 561]61].
Because these sequences are located on separate BAC clones that map to single chromosomes, they are likely to represent a real duplication and translocation event rather than an artifact caused by repetitive elements.
However, there are many cases where multiple probe sets map to single genes.
This procedure is designed to remove multiple probe sets that map to single genes; it reduced the total number of probe sets from 54614 to 18027.
What was surprising was that about 30% of the "unmapped" Preferred Terms for both indications and Adverse Events were found to map to single SNOMED CT concepts, indicating insufficient checking of these Preferred Terms during the MedDRA-UMLS curation process prior to characterizing them to distinct concepts in UMLS.
RNA-seq reads were aligned to the mouse reference genome by using bowtie (bowtie-bio.sourceforge.net; version 1.1.0) with parameters '-m 1 –v 2 –-best –-strata' in order to select reads that uniquely map to single repeat copies in the genome only.
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Multiple BAs can be mapped to single LSP or single BA can be mapped to single LSP.
However, such techniques have poor bandwidth utilization as multiple bits are mapped to single narrow pulse.
When multiple BAs are mapped to single LSP, the method is called E-LSP (EXP is used to specify PHB) and L-LSP when single BA is mapped to single LSP [8].
Each of these sequences mapped to single regions on different wasp chromosomes but not to PSR.
Only reads that mapped to single unique position on the genome were used.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com