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Specific DA-dependent behaviors may map to discrete sets of DA neurons.
It has been reported that variable genes (absent or highly divergent) in the Campylobacter genome map to discrete areas, termed variously plasticity regions, hypervariable regions or plasticity zones [ 16, 17, 21, 29].
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Shah et al.[17] propose a selection protocol where metrics of nodes are mapped to discrete timers.
Using the populations of two retinal interneurons, the horizontal cells and the cholinergic amacrine cells, we present in further detail examples where the variation in neuronal number, as well as the variation in mosaic patterning or in laminar positioning, each maps to discrete genomic loci where allelic variants modulating these features must be present.
Thus, EMG patterns were mapped to discrete font characters.
We wondered if PDF's various circadian functions might be mapped to discrete subclasses of PDF-expressing neuron using targeted RNA-interference (RNAi) knockdown of PDF expression.
In mice, we find suggestive evidence that for hundreds of gene expression traits, robustness is polymorphic and can be genetically mapped to discrete genomic loci.
The mapping results showed that 66 such transcripts were reliably mapped to discrete genomic locations each with a single gene annotation in B. distachyon (coverage ≥ 90%%, mean identity 87%%) (Fig. 3a).
Essentially, mRNA levels can be treated as a quantitative phenotype and as such can be mapped to discrete genomic regions (genetic loci) that harbor DNA sequence variation affecting gene expression.
Figure 1 shows the distribution of mean growth rates across at least three separate experiments (the number of experiments was larger for agents in multiple libraries) for each of the 1,398 agents that could be mapped to discrete concepts in SemMedDB.
The top associations in all classical class I genes mapped to discrete residues in the binding grooves of the HLA molecule: HLA-A position 62 (p = 3.3 × 10−76 with HIV Nef 135), HLA-B position 70 (p = 7.1 × 10−57 with HIV Gag 242), HLA-C position 99 (p = 5.4 × 10−63 with HIV Nef 70).
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