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Annotated sequences provide genomic bounds to which one can either map the sequence reads directly or within which one can sum all the mapped reads to generate transcript counts.
We are also developing biophysical models that can map the sequence of a genetic part (e.g., a ribosome binding site) to its function.
Longitudinal investigations using structural magnetic resonance imaging (MRI) provide a framework to map the sequence of neuroanatomical changes at all levels of this model.
For example, it may not be possible to map the sequence of a synthetic peptide to a region of the genome that can be assessed for conservation across species.
This last matrix, in turn, gives the coordinates of the active sequences in the active space formed by the eigenvectors (also called principal components) of S. We can map the sequence space of the human GPCRs onto the 3D space formed by the three components with the largest eigenvalues.
The second approach attempts to map the sequence reads to a position within a reference genome.
Similar(40)
This version was used to map the sequences around small RNA reads to identify structures consistent with miRNA precursors (according to prediction programmes detailed below).
Eland_extended algorithm was used to map the sequences to human genome (hg18).
To integrate this genetic map with the BAC-based physical map, the sequences of genetic markers were aligned with BES from the physical map using BLAST.
BLAT was used to map the sequences to the reference genome.
For such a large number of the sequences, BLAST tools are too slow to map the sequences to target genomes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com