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Here we combined systematic perturbation and direct lineaging to map the regulatory landscape of lineage differentiation in early C. elegans embryogenesis.
Experiments are performed to map the regulatory network data of S. cerevisiae to A. thaliana and analyze the results.
Overall, our metabolomic analysis demonstrates the importance of MYC2 in the regulation of plant's metabolome and when these metabolomic features are annotated, it will be possible to precisely map the regulatory role of MYC2 on plant defense and developmental responses.
As it becomes increasingly practical to map the regulatory linkages in GRNs from large-scale functional sequencing data, the challenge of modeling and predicting the dynamics of GRNs becomes ever more pressing.
ChIP is now routinely used to map the genomic distribution of transcription factors, chromatin remodelling factors, and histone modifications in numerous cell types and organisms, and it is a technique central to the efforts of large-scale genomics consortia to map the regulatory genome.
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GWAS can guild the genetic variations with the high-density SNP markers for mapping the regulatory locus of these traits.
The major goal for plant breeding is to select the best progenies with the desired traits, and GWAS can guild the genetic variations with the high-density SNP markers for mapping the regulatory locus of these traits.
Using the IPA platform, we mapped the regulatory networks significantly enriched with Genes of Interest (GoI).
Smemo and colleagues [ 102] considered the wider regulatory landscape of FTO and mapped the regulatory interactions between genomic loci using 3C.
A recently study in human B cells which maps the regulatory elements that influence radiation-induced changes in gene expression indicated that nearly all the strong regulators act in trans to influence the expression of their target genes [ 30].
First, we confirmed that the same mRNA isoforms were expressed in G2 and M. Furthermore, we mapped the regulatory element in the Emi1 UTRs, and found that the translational repression was conferred by the 3′UTR of Emi1 alone, which is identical in all Emi1 mRNA isoforms.
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