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In this way, FCS allows us to map the receptor density profiles according to oligomerization and activation state with higher precision than classical methods like immunoblots.
In the current study, we utilized chimaeric orexin receptor approach to map the receptor areas contributing to the selectivity of the classical antagonist, SB-334867, for OX1 receptors.
This strategy was employed, for example, to map the receptor binding site on transferrin (25).
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By dedicated clinical study materials from various patient groupings our objective is to map the receptor-ligand interactions.
This was followed by further studies on PfRH1 [22] and PfRH4 [24], which mapped the receptor binding region by analyzing the binding activity of several overlapping fragments of the PfRH proteins.
The principal components (PC) obtained from mapping the receptor Cα atoms of all the simulated trajectories were used to project the trajectories of a particular receptor system.
This sequence was then used to isolate, clone and hence physically map the ryanodine receptor gene (RYR1) in humans (MacLennan et al. 1989) and pigs (Harbitz et al. 1990).
Starting from a previous design (1), different structural variables have been mapped on the receptor frame.
Electrostatic, desolvation energies and atom type affinity grid maps on the receptor were previously calculated with Autogrid [38].
The R131H (rsubstitutionbstitutiof oFcγRIIaIa, a low-affinity IgG receptor that is widely expressed by diverse leukocyte types, maps to the receptor interface interacting with the Fc region of IgG and determines the affinity of FcγRIIa for human IgG subclasses [ 17].
The Brookhaven group used the scanner to map the dopamine receptors throughout the entire brains of of moving rats for the first time.
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