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To map the putative contact points of the protein on the IRF2 5' UTR we have performed primer extension inhibition assay.
The superimposition of LGI1 and the complex of WDR5 with its ligand (PDB code: 3EMH) allowed us to map the putative binding site of a ligand on the top surface of the EPTP domain (Figure 7).
In the consensus map, the putative location of PM3n was mapped at the distal end of LG11.
The program PEPSURF (http://pepitope.tau.ac.il/) was used to map the putative mimotope selected by phage display in the three-dimensional protein structure of the protein [ 29].
A combination of array CGH and PCR was utilized to map the putative breakpoints in five of the six probands (Fig. 2).
This region must be enriched in SNPs to locate precisely one or more responsible polymorphisms associated to the trait and further investigation should be carried out to fine map the putative gene responsible for the trait variation.
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We first computationally mapped the putative epitopes of the M using the Jameson-wolf algorithm [61] and predicted the region with the highest antigenic index.
Moreover this observation emphasises the need for mapping the putative flanking hairpin-like structures as such structures are a prerequisite for the postulated rolling-hairpin replication mechanism of HBoV.
At this chromosomal region Chettouh et al. [33] mapped the putative loci for intrauterine and postnatal growth retardation, microcephaly, low-set ears, cleft palate and mental retardation in monosomy 21.
By contrast, a strong consensus motif emerged when we mapped the putative cleavage sites in our set of 39 Ire1- and ER stress-dependently twofold down-regulated transcripts.
Where possible, candidate sex genes were mapped to determine if any map to the putative sex determining region on the rainbow trout sex chromosomes.
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