Sentence examples for map the causative from inspiring English sources

Mycobacterium avium subsp. paratuberculosis (MAP), the causative agent of Johne disease in ruminants, has been incriminated as the cause of Crohn disease in humans.

Sensitive real-time sequence detection methods based on two different chemistries were developed for Mycobacterium avium subsp. paratuberculosis (Map), the causative agent of Johne's disease in cattle.

Mycobacterium avium subspecies paratuberculosis (MAP), the causative agent of Johne's disease (JD) in animals, has also been linked with Crohn's disease in human beings.

Consequently, M. bovis detection is confounded by background infection with M. paratuberculosis (MAP), the causative agent of JD.

To map the causative mutation, p23-ST1 mice (B6 genetic background) were outcrossed with C3H mice, because of their genealogical distance and similarities in ventricle size (Supplementary Table S1).

The extent of LD between breeds such as Holstein and Jersey is such that markers will only be validated across breeds if they are very close to the causative mutation [22], so the validation strategy we have used should map the causative mutation to a small genomic interval (eg. Figure 4).

Together with large-scale phenotyping approaches, this enables researchers to start mapping the causative mutations for complex industrially relevant traits, such as ethanol tolerance.

Therefore, using the relative fitness of a mutant strain to determine the best experimental design is expected to underestimate the true power for mapping the causative mutation in that strain.

A genome-wide screen of DFNA20 localized candidates to 17q25.3 [ 26] and mapped the causative missense mutations to highly conserved actin domains of the gamma-actin gene (ACTG1) [ 27, 28].

The presence of a relatively large QTL segregating on chromosome 15 suggested that we had mapped the causative mutation, but we could not exclude the possibility that the genetic effect arose from a naturally occurring polymorphism between BALB/cAnN and C3H/HeH.

MAP is the causative agent of paratuberculosis (Johne's disease); a chronic granulomatous enteritis causing malnutrition, therapy-resistant diarrhea, emaciation, low milk yield, and ultimately death (Clarke and Little 1996).