Sentence examples for map the calpain from inspiring English sources

To map the calpain cleavage site, we implemented two approaches.

To precisely map the calpain cleavage site, we performed in vitro calpain cleavage reactions using purified recombinant HIS6-SMN/GST-Gemin2 heterodimers followed by mass spectrometric analysis of the C-terminal cleavage product.

Protein 2.2 is distinct from the calpain fragment based on peptide maps and reaction with domain-specific antibodies.

H.M. and S.H. carried out the calpain and ubiquitination analyses.

Immunofluorescence analyses revealed that calpain-1 localizes to filopodia (Fig. 7d) and ratiometric FRET analyses of cells co-expressing a calpain sensor33 and MYO10-mCherry demonstrated that calpains are active within filopodia (Fig. 7e; controls related to the use of the calpain FRET probe are shown in Supplementary Fig. 11).

Calpain inhibitors inhibit the calpain activity, resulting in reducing the calpain-meditated apoptosis[10].

The calpain inhibitor calpeptin prevents MV-induced muscle atrophy.

In contrast, animals pretreated with the calpain inhibitor showed minimal evidence of apoptosis.

Our data suggest that a complimentary cross talk exists between the calpain system and the UPP.

The calpain inhibitor SNJ-1945 was kindly provided by Senju Pharmaceutical Co., Ltd.

The calpain activity and calpain-II (m-calpain) protein (but not calpain-I (µ-calpain)) level could also be increased by honokiol.