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The broad range of genes that respond to environmental stress is evident in this genome-wide map of genes that are up or down-regulated when fruit flies are exposed to the heavy metal cadmium.
(C) Heat map of genes differently expressed in Ponatinib-treated LM2 cells, the related genes expression in ABL1/ABL2 or double-knockdown in LM2 cells were also shown.
The real race, then, may not be between Celera and the Human Genome Project, both of which are producing a map of genes without knowing what the genes do.
Several years ago, we published the first sequence-based map of genes with mutant phenotypes in Arabidopsis, which we concluded would eventually replace the classical genetic map [14].
We integrated microarray data obtained from the expression module map of genes up-regulated in cancer [51] and data derived from the A549 cells over-expressing a constitutively active form of STAT3 [52].
Interaction map of genes affected by mutation in R57. Figure S2.
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(c) Heat map of gene expression in TSA tumours 24 h after radiation in vivo (n=3).
e, Enrichment map of gene sets affected by SCNAs in Group 3 versus Group 4. Network analysis of Group 3 and Group 4 SCNAs illustrates the different pathways over-represented in each subgroup.
A global map of gene expression for the Arabidopsis root has recently been published that consists of high-resolution spatial- and temporal-expression profiles.
To gain context for their findings, the researchers considered their gene-prediction results alongside a map of gene expression in the developing brain compiled by neuroscientists at the Yale University School of Medicine.
The Allen Institute for Brain Science has launched its map of gene expression in the human brain.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com