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The CAVER program is based on the Dynamic Map Ensemble (DyME) application program.
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For high-variance base learners (e.g., models in which QTL are included at low selection stringency with dense maps), ensembling might provide a reduction in variance of predictions.
Gene expression probes were mapped to ensemble genes using ensembl build 37 assembly 55.
Complementary genome-wide studies will be required in the future to comprehensively map the ensemble of histone modifications regulating genetic programs in cognitive and other biological processes.
Any other kinds of gene IDs can be mapped to Ensemble Genome IDs using the 'ID mapping' tool.
The long-range Ising model can be solved by mapping the ensemble onto to a single large spin.
For comparison of evolutionary rates, gene datasets were first mapped to ensemble proteins.
Of the resulting subset, we used in the comparison genes whose TaqMan probe IDs unambiguously mapped to Ensemble gene IDs (686 genes).
In the mRNA data, probe set identifiers (IDs) were mapped to ensemble gene IDs and mean expression level from multiple probe sets corresponding to the same gene was used to represent its expression level.
The prediction performance of the three primary maps and the two ensemble maps was compared with an independent validation dataset consisting on 100 observations from the French soil monitoring network.
The objectives of this paper are to design and validate machine learning based-risk maps using ensemble-based modelling with an integrative approach.
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