Sentence examples for map a phenotype-causing from inspiring English sources

The method can also be used to map a phenotype-causing deletion [5].

However, to avoid multiple WGS runs and/or if multiple alleles are not available, it may be desirable to first map the phenotype-causing variant to a chromosomal interval.

In such cases, little if any mapping is required since the phenotype-causing mutant locus will be one of the few, if not only loci found to be mutated in both WGS datasets.

To assess the feasibility of segregant-pool-based mapping of phenotype-causing genes in natural strains of fission yeast, we investigated the cause of a maltose utilization defect (Mal-) of the S. pombe strain CBS5557 (originally known as Schizosaccharomyces malidevorans).

As mutagenized strains contain a significant mutational load, it is often still necessary to map mutations to a chromosomal interval to elucidate which of the WGS-identified sequence variants is the phenotype-causing one.

A heat map illustrates the similarities between the transcription profiles of hINSWT and the control and confirms at the molecular level the lack of a visible phenotype caused by hINSWT expression.

The phenotype is a milder SBBS phenotype caused by haploinsufficiency.

In the case presented here, it provided a ∼2 Mb mapping interval and limited the candidate phenotype causing mutations to only 3 protein changing variants.

We identified a rice mutant oslap6 with complete male sterile phenotype caused by defects in pollen exine formation.

The validated polymorphisms were used to genetically map known mutations causing visible phenotypes thus demonstrating the effectiveness of the polymorphisms in linkage mapping studies.

A completely bijective mapping would cause a one-to-one mapping from a different genotype to a different phenotype, while the standard genetic code maps 64 codons to 20 amino acids and the stop signal.