Sentence examples for many upstream receptor from inspiring English sources

AKT can be activated by many upstream receptor tyrosine kinases and this is apparent in the observation that 11 of the 46 (24%) samples demonstrated activated AKT in the absence of HER-2/ neu overexpression.

In many upstream areas cut off from the ocean by dams, sturgeon simply live upstream of the dam.

Discovering the upstream receptor for Hpo signaling in follicle cells will be of great interest.

Stat3 can mediate signaling through upstream receptor tyrosine kinases such as epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor (PDGR) as well as upstream non-receptor tyrosine kinases such as Abl and Src-related kinases.

Runx2 responds to many upstream molecules, such as BMP-2 and MAPK [ 43].

Autophagy is a complicated process that involves input from many upstream regulatory signaling pathways [15].

Components of these pathways are mutated or abnormally expressed in many tumour types and mutations of upstream receptors, such as EGFR, transmit their signals through these cascades.

FAs are regulated by complex mechanisms, including upstream receptors that impact on FA signalling, for example, integrins, ErbB, Met and PDGFR, as well as many kinases and adaptor proteins, including Src, FAK, Paxillin, p130Cas, Crk, Arp2/3, Rho-GTPases and others (Zaidel-Bar et al, 2003; Wehrle-Haller, 2012).

AT1R belongs to the group of GPCRs that act as upstream receptors of Hippo signaling.

Both domains form the TRAF domain responsible for self-association and for interaction with upstream receptors.

7 Notably, KRAS and PIK3CA pathways can also be activated by other upstream receptors.