Sentence examples for many underlying genetic from inspiring English sources

Multidimensional adaptive landscapes (i.e. which represent fitness as a function of many underlying genetic variables) typically have extensive ridges of high fitness (they are 'holey'), facilitating movement across the landscape (Gavrilets 1999).

Although many underlying genetic signatures have been successfully identified for Mendelian disorders (Hamosh et al., 2005), not many genetic risk factors for complex diseases have been discovered and confirmed.

The zebrafish system has been especially powerful in the identification of developmental phenotypes, caused by N-ethyl N-nitrosourea (ENU) and insertional mutagenesis, and many of the underlying genetic mutations have been identified [ 4- 8].

However, in many POF cases, the underlying genetic variants or mutations are unknown.

But he believes that in many cases there is an underlying genetic predisposition that responds to environmental stimuli in such a way that once-normal behavior turns into something pathological.

For instance, most of the information here implies that the individual variables are so complex that each is an actually a compound of several, perhaps many, characters (resulting from different underlying genetic, developmental and functional mechanisms).

In many of the affected cases, the underlying genetic risk architecture for these WMN abnormalities remains unknown.

Bipolar disorder, like many other mental disorders, has an underlying genetic component that increases the vulnerability to, and triggers, the disorder, frequently in adolescence or early adulthood, and often in response to stressful life experiences (Goodwin and Jamison 2007).

Genome-wide association studies (GWASs) are an optimal design for discovery of disease risk loci for diseases whose underlying genetic architecture includes many common causal loci of small effect (a polygenic architecture).

The underlying genetic defect in many patients remains unknown and there are no effective treatments (1, 2).

By doing so, they showed that many disorders share a set of underlying genetic risk variants and that similar diseases are caused by similar genes.