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Whilst early detection can lead to effective treatment, and androgen deprivation therapy has a high response rate, many tumours develop towards hormone-refractory prostate cancer, for which there is no successful treatment.
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Endocrine therapy is the treatment of choice for hormone-sensitive breast cancer; however, over time many patients become resistant as tumours develop the ability to escape the antiproliferative effects of endocrine therapy (Martin et al, 2003).
Many patients with central nervous system (CNS) or non-CNS tumours develop cognitive problems during the course of their disease that can result in diminished functional independence.
Vogelstein's research made it clear that tumours develop as a result of the sequential accumulation of mutations in proto-oncogenes, tumour-suppressor genes, and mismatch repair genes.
If these checkpoints are themselves faulty, uncontrolled division may lead to tumours developing.
Dr Claus thinks she has identified, in those who have had dental X-rays often, a significant rise in the admittedly small risk of developing a brain tumour.In this section Misery index Little and not often, please To dye for Fun run ReprintsIn rich countries, five men in every 200,000, and twice as many women, develop tumours called meningiomas that affect the membranes surrounding the brain.
It can be used for patients with all tumour types (compared to having to develop many tumour-specific questionnaires).
These metastases to distant tissues generally develop in a haphazard manner, although many tumours display characteristic patterns of spread.
A generic questionnaire has advantages: it can be used for patients with all tumour types and makes developing many tumour-specific questionnaires superfluous.
However, even in early stage OSCC, many patients develop recurrent tumours that once developed indicate a poor patient prognosis.
It is not known how many tumours without chromosome 3 loss and 8q gain at the time of treatment would have developed these changes is left untreated.
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