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On brain scans, Avastin seems to shrink many tumors.
Many tumors express high levels of nonfunctional mutant p53.
Dr. Folkman's team had found that angiogenesis was essential to the survival of many tumors.
But many tumors defy chemotherapy: they shrink temporarily and then grow back.
"We don't really understand how tumors renew themselves, or how to treat many tumors," he says.
But they are not always effective because many tumors contain central zones devoid of blood and oxygen.
Radiotherapy is one of the most effective non-surgical treatments for many tumors.
Hypoxia occurs in many tumors and reduces the effectiveness of radio- and chemotherapy.
MicroRNAs regulate post-transcriptomic landscape in many tumors including renal cell carcinoma.
Immunotherapy is a novel treatment for many tumors including prostate cancer.
Many tumors evolve sophisticated strategies to evade the immune system, and these represent major obstacles for efficient antitumor immune responses.
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CEO of Professional Science Editing for Scientists @ prosciediting.com