Cancer immunotherapy has become a promising therapeutic modality in many tumor types.
Infiltration of regulatory T (Treg) cells into many tumor types correlates with poor patient prognoses.
Given that many tumor types rely on oxidative metabolism, glucose flux is not necessarily coupled to oxidative glucose metabolism.
Cancer-associated fibroblasts (CAFs) are the dominant cell type within the reactive stroma of many tumor types.
In addition to normal tissues, MAGE-F1 is expressed in many tumor types including ovarian, breast, cervical, melanoma and leukemia.
EGFR blockers like Iressa had far broader potential than Herceptin, since EGFR is abundant in many tumor types.
Evidence of a crosstalk between HH-GLI and other oncogenic signaling pathways has been reported in many tumor types, as shown by recent reviews.
Purpose: Tumor hypoxia has been purported to be an important biologic factor in the failure of radical radiotherapy to achieve local control in many tumor types.
New strategies to improve cancer control are needed and agents targeting the immune system have shown encouraging results in many tumor types.
Previous reports have shown the LOI of H19 in many tumor types (Table S3).
Ezrin, whose expression correlates with progression in many tumor types, is involved in multiple metastatic pathways [16] [18].
