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Gingrich then asked how many trials would have to be done until one might actually work.
This is a good practical solution where the number of trials is already high, but this does not really say why the estimate should be good, how good it is supposed to be, or how many trials would be high enough.
It is improbable that so many trials would remain unpublished.
We cannot tell how many trials would have been sent to 'mainstream' journals and rejected and we would have expected to see them published in the home literature.
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(Turing says nothing about how many trials he would require.
At the same time, a move to conduct many more pragmatic trials would involve nothing less than a rethinking of how medical research is financed and managed.
Many more tests and trials would be needed.
But many test developers argue that trials would be too costly and time-consuming, so many tests are validated by reanalyzing patient data from old trials.
The trials would shortcut many of the rules that slow trials.
Many in Northern Ireland fear that trials would reopen the old wounds, destabilizing the peace process, all the more so as unionists have already begun clamoring for offsetting "justice" for themselves, in terms of the large numbers of their community who were killed by republican bombings, shootings and assassinations that were followed by amnesties under the Good Friday pact.
The restrictive inclusion criteria of most trials would exclude many HNSCC patients with co-morbidities due to chronic alcohol and nicotine consumption.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com